cytotoxic alkaloid — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T32291	Jineol	NSC694081,3,8-Quinolinediol,NSC 694081,NSC-694081	Others
	Jineol (NSC-694081) is a quinoline alkaloid from Scolopendra subspinipes. Jineol shows cytotoxic activity against the growth of human tumor cell lines in vitro.		Others
T3933	Jatrorrhizine	Yatrorizine,neprotin	MAO , 5-HT Receptor , Antibacterial , AChE
	Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits mo...		MAO , 5-HT Receptor , Antibacterial , AChE
T4912	Jatrorrhizine chloride	Yatrorhizine chloride,Neprotine chloride	Others , 5-HT Receptor , OCT , Antibacterial , AChE
	Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h...		Others , 5-HT Receptor , OCT , Antibacterial , AChE
T3380	Homoharringtonine	Myelostat,Ceflatonin,HHT,Omacetaxine mepesuccinate	STAT
	Homoharringtonine (HHT) is a natural alkaloid that inhibits the translation of proteins and is cytotoxic. Homoharringtonine acts on the ribosomes of tumor cells to inhibit the elongation step of protein translation, ther...		STAT
TN3013	4,5-Dimethoxycanthin-6-one	Methylnigakinone	P450 , Antibacterial , PDE
	4,5-Dimethoxycanthin-6-one is an alkaloid isolated from Picrasma quassioides BENNET (Simaroubaceae).4,5-Dimethoxycanthin-6-one was isolated from Picrasma quassioides BENNET (Simaroubaceae) with antimicrobial activity.4,5...		P450 , Antibacterial , PDE
T34252	Racemosidine A
	Racemosidine A is a cytotoxic bisbenzylisoquinoline alkaloid from the roots of Cyclea racemosa.
T30869	Chaetominine	NSC 746369,NSC-746369,NSC746369
	Chaetominine is a type of cytotoxic alkaloid obtained from endophytic Chaetomium sp. IFB-E015.
T39610	Guattegaumerine
	Guattegaumerine, a bisbenzylisoquinoline alkaloid, exhibits antimitotic, cytotoxic, and neuroprotective activities.
T38429	(+)-Intermedine
	(+)-Intermedine, a pyrrolizidine alkaloid (PA), shows remarkable cytotoxic activity against neural progenitor cells (NPCs).
T40133	Agrochelin
	Agrochelin, an alkaloid cytotoxic antibiotic, is synthesized via fermentation of a marine Agrobacterium sp. This compound demonstrates cytotoxic activity against tumor cell lines.
T29434	4-Desacetylvinblastine hydrazide	DAVLBH,Deacetylvinblastine hydrazide,Desacetylvinblastine hydrazide
	Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.
T82970	Aristolactam A III	Aristololactam A III
	Aristolactam A III (Aristololactam A III) is an alkaloid that exhibits potential cytotoxic properties. It can be extracted from the herb Houttuyniae herba [1].
T75698	Xylopine
	Xylopine, an aporphine alkaloid, exhibits cytotoxic effects on cancer cells by inducing oxidative stress, provoking G2/M cell cycle arrest, and triggering apoptosis [1].
T36101	Psychotridine
	Psychotridine is an alkaloid that has been found inP. forsterianaand has diverse biological activities.1,2,3It inhibits ADP-, collagen-, or thrombin-induced aggregation of washed isolated human platelets with IC50values ...
T37452	Stephacidin B
	Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, includ...